Hailed as one of the best rom-coms in recent years, The Big Sick was written by the married couple Kumail Nanjiani and Emily V Gordon, and is based on the story of their courtship. Nanjiani plays himself, while Zoe Kazan is Gordon – and the plot is "the kind of sweetly funny movie love story that's so bizarre that it has to be real", according to The Wrap. Meeting when Nanjiani was an aspiring stand-up comedian, they have to navigate his parents – traditional Muslims from Pakistan – and a mystery illness leaves Gordon in a medically-induced coma.
《大病》被誉为近年来最优秀的爱情喜剧电影之一，该片由库梅尔•南贾尼和艾米丽•V•戈登夫妇基于两人的爱情故事改编而成。南贾尼饰演他本人，而佐伊•卡赞饰演艾米丽•V•戈登。据《The Wrap》杂志称，这是一部“甜蜜中带着诙谐的爱情故事片，荒诞却又真实”。电影中南贾尼是一个胸怀大志的脱口秀喜剧演员，他和戈登不得不投奔他的父母（来自巴基斯坦的传统穆斯林），而戈登得了一场奇怪的大病，并陷入由药物引发的昏迷。