The seven astronauts arrived at the launching site, soon after US space agency NASA began the countdown for Monday's launch.
Scott Altman is Commander of Space shuttle Atlantis.(www.hXen.com)
"It's great to be here, at last. Lining up for launch on Atlantis, it's been a long road to get here, we're all thrilled."
Atlantis was supposed to be launched last year, but an accident on Hubble delayed the mission.
If the launch succeeds this time, the crew would have the chance to perform 5 space walks.
They will replace old cameras, and try to repair two failed instruments, something never attempted before at Hubble.